Named after pioneer Australian geologist Reverend William Branwhite Clarke, the centre will exhibit more than 24,000 specimens in the Economic Rocks and Mineral collection together with 44,000 macrofossils from the Palaeontology Collection.
It will also house more than 1 million metres of drill core.
After being officially reopened at 11am on Monday December 10 it can be visited at 947 - 953 Londonderry Road in Londonderry, West Sydney.